منابع مشابه
Transcriptional segregation
Soluble prion protein makes mice unsteady. Li nd qu is t/A A A S version: the infectious, detergent-resistant, plaque-forming fibrillar PrP Sc seen in diseased brains of scrapie-infected sheep and mad cows. Instead, Jiyan Ma, Robert Wollmann (University of Chicago, Chicago, IL), and Susan Lindquist (MIT, Cambridge, MA) point the finger at cytosolic PrP. Minor misfolding events probably lead to ...
متن کاملSpatial Segregation in Demography: A Short Review
Abstract. Spatial has always been an inherent component of demography, and demographic processes are inherently spatiotemporal. Recognizing the importance of spatial in general and spatial segregation in particular in demographic analysis has created new positions in demography and its conceptual and analytical frameworks. The notion of spatial segregation refers to the distribution of social...
متن کاملHistone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.
Position-effect control at the silent mat2-mat3 interval and at centromeres and telomeres in fission yeast is suggested to be mediated through the assembly of heterochromatin-like structures. Therefore, trans-acting genes that affect silencing may encode either chromatin proteins, factors that modify them, or factors that affect chromatin assembly. Here, we report the identification of an essen...
متن کاملTranscriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila.
Segregation of a single neural precursor from each proneural cluster in Drosophila relies on Notch-mediated lateral signalling. Studies concerning the spacing of precursors for the microchaetes of the peripheral nervous system suggested the existence of a regulatory loop between Notch and its ligand Delta within each cell that is under transcriptional control. Activation of Notch leads to repre...
متن کاملFission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation.
In the fission yeast Schizosaccharomyces pombe genes are transcriptionally silenced when placed within centromeres, within or close to the silent mating-type loci or adjacent to telomeres. Factors required to maintain mating-type silencing also affect centromeric silencing and chromosome segregation. We isolated mutations that alleviate repression of marker genes in the inverted repeats flankin...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1593rr4